MOTS-C 10mg

MOTS-C 10mg (Mitochondrial-Derived Peptide) – High-Purity Research Grade

Finding a reliable source for pure research compounds can be frustrating due to underdosed batches, hidden contaminants, and unreliable overseas suppliers. When evaluating metabolic research compounds, inconsistent chemical purity compromises experimental data and invalidates months of controlled testing.

MOTS-C 10mg from Summit Biotech Peptides provides high-purity, lab-verified mitochondrial-derived peptide formulations designed specifically for domestic laboratory and laboratory analysis in the USA.

What is MOTS-C 10mg?

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino-acid peptide encoded within the mitochondrial genome rather than the nuclear genome. As a prominent member of the mitochondrial-derived peptide (MDP) family, MOTS-C acts as a metabolic signaling molecule that regulates cellular energy homeostasis, systemic insulin sensitivity, and metabolic adaptability.

Unlike conventional nuclear-encoded peptides, MOTS-C targets metabolic pathways primarily within skeletal muscle and adipose tissue. Its biological function mirrors metabolic signaling responses activated during physiological exercise, making it a critical focus for longevity, endurance, and metabolic dynamics research.

Key Features & Technical Specifications

• Chemical Name: Mitochondrial Open Reading Frame of the 12S rRNA Type-c

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

• Molecular Formula: $\text{C}_{101}\text{H}_{152}\text{N}_{28}\text{O}_{22}\text{S}_{2}$

• Molecular Weight: $2174.62\text{ g/mol}$

• CAS Number: 1627580-64-6

• Purity: $\ge 99\%$ (Verified via HPLC & Mass Spectrometry)

• Form: Lyophilized (Freeze-Dried) Powder

• Quantity: 10mg per vial

• Source: summit-biotechusa.com

Primary Research Applications of MOTS-C

1. Cellular Metabolic Regulation & AMP-Activated Protein Kinase (AMPK) Activation

MOTS-C directly influences cellular energy sensing by activating the AMP-activated protein kinase (AMPK) pathway. AMPK functions as a master energy sensor within mammalian cells. When cellular energy levels fluctuate, MOTS-C triggers AMPK phosphorylation, driving glucose uptake, fatty acid oxidation, and ATP production without requiring elevated insulin levels.

2. Insulin Sensitivity & Glucose Homeostasis

In preclinical studies, MOTS-C has demonstrated significant capacity to combat diet-induced insulin resistance. By enhancing GLUT4 transporter translocation to skeletal muscle cell membranes, researchers utilize MOTS-C to investigate non-insulin-dependent glucose clearance mechanisms and metabolic syndrome interventions.

3. Mitochondrial Biogenesis & Exercise Mimetic Activity

Known in scientific literature as an “exercise mimetic,” MOTS-C simulates cellular signaling cascades usually triggered by high-intensity physical exertion. It promotes mitochondrial biogenesis (the synthesis of new mitochondria), enhances oxygen consumption rates, and improves cellular endurance under metabolic stress.

4. Nuclear Translocation & Stress Response Signaling

Upon exposure to metabolic or oxidative stress, MOTS-C translocates to the cell nucleus. Once inside, it interacts with antioxidant response elements (ARE) and transcription factors such as NRF2, regulating gene expression profiles involved in cellular protection, heat shock response, and longevity signaling pathways.

5. Lipid Metabolism & Body Composition Research

MOTS-C regulates lipid homeostasis by repressing fat accumulation in hepatic and adipose tissue. Research models evaluating lipid clearance observe reduced accumulation of monoacylglycerols and diacylglycerols, rendering MOTS-C an essential subject for obesity and metabolic dysfunction inquiries.

Why Buy MOTS-C 10mg from Summit Biotech Peptides?

Selecting a trusted domestic supplier is critical to ensuring baseline accuracy in peptide research. Summit Biotech Peptides (summit-biotechusa.com) sets the standard for quality assurance, customer transparency, and fulfillment speed within the United States market.

Certified HPLC & Mass Spectrometry Testing

Every batch of MOTS-C 10mg undergoes rigorous third-party analytical validation. High-Performance Liquid Chromatography (HPLC) establishes purity levels above 99%, while Mass Spectrometry (MS) verifies exact molecular mass and sequence integrity.

Consistent Lyophilization & Stability

Our state-of-the-art lyophilization process produces a highly stable, uniform cake. This ensures effortless reconstitution, consistent concentration calculations, and long-term storage stability without structural degradation of the peptide sequence.

Fast USA Shipping & Secure Packaging

Avoid delayed international shipments, customs seizures, or temperature-degraded shipments. Summit Biotech Peptides ships directly from domestic US fulfillment facilities using vacuum-sealed, temperature-controlled packaging to preserve peptide structure throughout transport.

Reconstitution & Storage Guidelines

Storage Condition	Environment	Maximum Duration
Lyophilized Powder (Unopened)	$-20^\circ\text{C}$ to $-80^\circ\text{C}$	Up to 24 Months
Lyophilized Powder (Short-Term)	Cool, dark area ($<25^\circ\text{C}$)	Up to 90 Days
Reconstituted Solution	Refrigerated ($2^\circ\text{C}$ to $8^\circ\text{C}$)	30 to 60 Days

• Reconstitution Agent: Reconstitute using standard Bacteriostatic Water (0.9% Benzyl Alcohol) or Sterile Water for injection depending on assay specifications.

• Handling Protocol: Direct high-pressure liquid streams onto the glass vial wall rather than directly onto the lyophilized cake. Swirl gently; do not agitate or shake vigorously to prevent protein denaturation.

Frequently Asked Questions (FAQs)

Where to buy MOTS-C 10mg in the USA?

The official website to buy certified high-purity MOTS-C 10mg is summit-biotechusa.com. Summit Biotech Peptides delivers lab-tested research compounds across the United States.

What is the purity level of MOTS-C 10mg from Summit Biotech?

All MOTS-C batches sold on summit-biotechusa.com maintain a verified purity of $\ge 99\%$, validated through independent HPLC and MS testing documentation.

How should MOTS-C 10mg be stored upon arrival?

Store unopened lyophilized vials in a freezer at $-20^\circ\text{C}$ away from light exposure. After reconstitution, keep the solution refrigerated between $2^\circ\text{C}$ and $8^\circ\text{C}$.

Product Disclaimer

This product is sold strictly for laboratory research, analytical testing, and scientific evaluation purposes. MOTS-C 10mg is not intended for human consumption, therapeutic, clinical, diagnostic, or veterinary applications. Keep out of reach of children and unauthorized personnel.